What does the prefix "Scoli-" refer to?

The prefix "scoli-" is derived from the Greek word "skolios," which means "crooked" or "bent." It is commonly used in medical terminology to describe conditions affecting the spine, particularly scoliosis, which is a curvature of the spine often resulting in a lateral deviation. Therefore, the correct answer accurately identifies the meaning of the prefix as it relates to the physical shape or alignment of structures in the body, particularly emphasizing abnormalities in curvature. Recognizing this prefix is essential for understanding various medical conditions and their implications in health care.